Secondary :
- To study age wise distribution of various endometrial pathologies.
- To study age wise clinical presentation (symptomatology) in patients
with AUB.
- To assess the feasibility and compare different techniques of
collecting endometrial sample.
Design and setting: A single center prospective cross sectional
study at teaching institute
Population/Sample : 150 females from 18-70 years presenting with
abnormal uterine bleeding. Endometrial sample was obtained either by OPD
Pipelle brush or Surgical Dilatation and Curettage method or
hysteroscopy.
Outcome measures : Endometrial sampling methods used, Endometrial
Pathology, Age groups wise clinical and pathological correlation,
Feasibility of technique used. Statistical Analysis was done by using
Epi-Info-7 software.
Results : Commonest age group presenting with AUB was 41-50
(40%) years ,64 % were para 3 or more, Proliferative and secretary
changes, 53(35.3%) and 24(16%) cases while endometrial hyperplasia
without atypia 18 (12%) cases and with atypia7cases(4.7% ),endometrial
carcinoma 5 cases(3.3%) while endometrial polyp was seen in 8
cases(5.3% ). Heavy menstrual bleeding with normal duration was
commonest presentation in 64%. Endometrial sampling technical failure
was seen in 2 cases with pipelle biopsy while in 7 cases inadequate
sample was obtained with pipelle and dilatation and curettage. Uterine
perforation was seen in one case which was managed conservatively.
Conclusion: T echnical failure and inadequate sample needs to be
addressed considering background high risk factors, TVS imaging and
repeat sample and use of hysteroscopy may be offered case to case basis.